SCHEMBL9056103

SCHEMBL9056103

NC(=O)Nc1cccc(C(=O)NCC(=O)OCc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.60
RAB9A P51151 3/20 0.56
LMNA P02545 1/20 0.51
MAPT P10636 3/20 0.51
TDP1 Q9NUW8 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
NR1H4 Q96RI1 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
KDM1A O60341 1/20 0.48
MAOA P21397 1/20 0.48
KDM1B Q8NB78 1/20 0.48
RCOR1 Q9UKL0 1/20 0.48
SPHK2 Q9NRA0 1/20 0.47
MGLL Q99685 1/20 0.47
STAMBP O95630 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435665 0.84 GLA (0.56) GLARAB9ALMNAMAPTTDP1
SCHEMBL8384393 0.83 GLA (0.65) GLARAB9ALMNAMAPTMEN1
SCHEMBL22416771 0.82 GLA (0.68) GLARAB9ALMNAMAPTMEN1
SCHEMBL27471805 0.82 RAB9A (0.76) RAB9ALMNAMAPTTDP1KMT2A
SCHEMBL5948139 0.82 GLA (0.74) GLARAB9ALMNAMAPTTDP1
Hydrochloric Acid SCHEMBL27455337 0.81 RAB9A (0.74) RAB9ALMNAMAPTTDP1KMT2A
SCHEMBL8385674 0.81 GLA (0.52) GLARAB9ALMNAMAPTTDP1
SCHEMBL6775393 0.81 PLA2G10 (0.49) LMNAMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL8534533 0.78 RAB9A (0.63) GLARAB9ALMNAMAPTMEN1
SCHEMBL6854023 0.77 ALDH1A1 (0.58) GLARAB9ALMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996004254-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-15 WO disclosed