Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335874 | 0.91 | PRMT5 (0.51) | GLAPRMT5WDR77RAB9AKAT6A | |
| SCHEMBL7425443 | 0.85 | RAB9A (0.71) | RAB9AKAT6AMAPTTDP1KMT2A | |
| SCHEMBL7145264 | 0.84 | MGLL (0.52) | RAB9AMGLLKDM1AMAOAKDM1B | |
| SCHEMBL9056103 | 0.84 | GLA (0.60) | GLARAB9AMAPTTDP1MEN1 | |
| SCHEMBL28321345 | 0.81 | MGLL (0.52) | RAB9AMAPTKMT2AMGLLNR1H4 | |
| SCHEMBL10160157 | 0.81 | SENP1 (0.55) | PRMT5WDR77RAB9AMAPTLMNA | |
| SCHEMBL15145016 | 0.81 | NPFFR1 (0.57) | GLARAB9AMAPTMEN1KMT2A | |
| SCHEMBL13359195 | 0.80 | PRMT5 (0.59) | PRMT5WDR77RAB9AKAT6AMAPT | |
| SCHEMBL31396764 | 0.80 | KMT2A (0.59) | PRMT5WDR77RAB9AKAT6AMAPT | |
| SCHEMBL8238491 | 0.80 | SYK (0.61) | RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |