Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056238 | 0.89 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2TP53KCNH2 | |
| SCHEMBL8801306 | 0.82 | PIM1 (0.37) | MAPK8SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL9048087 | 0.82 | KDM4E (0.41) | MAPK8SMN1; SMN2KCNH2ALDH1A1KDM4E | |
| SCHEMBL9055113 | 0.81 | MAPK8 (0.51) | MAPK8MAPK9NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9056323 | 0.81 | PIM1 (0.37) | MAPK8SMN1; SMN2KCNH2ALDH1A1KDM4E | |
| SCHEMBL8801570 | 0.79 | PIM1 (0.37) | MAPK8ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL8803705 | 0.79 | HDAC1 (0.38) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9043747 | 0.77 | TOP1 (0.51) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL8801060 | 0.76 | TOP1 (0.39) | SMN1; SMN2TP53ALDH1A1KDM4EPOLB | |
| SCHEMBL9055563 | 0.76 | MAPK8 (0.37) | MAPK8SMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |