Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 5/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057039 | 0.85 | MAPK8 (0.41) | MAPK8KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL9055411 | 0.85 | GAA (0.38) | MAPK8GAAMEN1KMT2AHDAC10 | |
| SCHEMBL9056323 | 0.81 | PIM1 (0.37) | MAPK8STAT3KDM4EALDH1A1PIM1 | |
| SCHEMBL8801306 | 0.78 | PIM1 (0.37) | MAPK8STAT3KDM4EALDH1A1PIM1 | |
| SCHEMBL9056459 | 0.76 | MAPK8 (0.42) | MAPK8GAAKDM4EALDH1A1HTT | |
| SCHEMBL9056243 | 0.76 | MAPK8 (0.40) | MAPK8KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8801570 | 0.75 | PIM1 (0.37) | MAPK8STAT3KDM4EALDH1A1PIM1 | |
| SCHEMBL8803705 | 0.75 | HDAC1 (0.38) | STAT3KDM4EALDH1A1PIM1HDAC6 | |
| SCHEMBL10912940 | 0.74 | ALDH1A1 (0.48) | MAPK8STAT3GAAKDM4EALDH1A1 | |
| SCHEMBL6215098 | 0.73 | PIM1 (0.43) | STAT3KDM4EALDH1A1PIM1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |