SCHEMBL9056250

SCHEMBL9056250

CC1(C)CC(=O)C(Cc2ccc(Cl)cc2)C1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.44
TSHR P16473 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRA5 P31644 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
FFAR1 O14842 1/20 0.39
ALDH1A1 P00352 1/20 0.38
TRPA1 O75762 1/20 0.37
CMA1 P23946 1/20 0.36
MAPT P10636 1/20 0.36
PPARG P37231 1/20 0.35
P2RX7 Q99572 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9056056 0.94 TSHR (0.46) MAOBTSHRGABRA1GABRA5SMN1; SMN2
SCHEMBL9331145 0.81 MAPT (0.50) MAOBTSHRGABRA1GABRA5SMN1; SMN2
SCHEMBL5350084 0.72 MAOB (0.40) MAOBTSHRSMN1; SMN2FFAR1ALDH1A1
SCHEMBL9126023 0.71 MAOB (0.46) MAOBTSHRSMN1; SMN2FFAR1ALDH1A1
SCHEMBL9147038 0.70 TRPA1 (0.40) MAOBTSHRSMN1; SMN2ALDH1A1TRPA1
SCHEMBL1784163 0.69 PTGS2 (0.56) MAOBTSHR
SCHEMBL9147334 0.69 PTGS1 (0.52) MAOBTSHRSMN1; SMN2ALDH1A1
SCHEMBL29169558 0.69 PTGS2 (0.56) MAOBTSHR
SCHEMBL15641193 0.69 MAOB (0.38) MAOBTSHRSMN1; SMN2FFAR1ALDH1A1
SCHEMBL9148468 0.69 HSD11B1 (0.40) MAOBTSHRALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996003390-A1 AZOLYLMETHYLCYCLOPENTANOL DERIVATIVES AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-02-08 WO disclosed