Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056823 | 0.87 | KDM4E (0.46) | KDM4EMAPTHTTALDH1A1GAA | |
| SCHEMBL9056342 | 0.83 | ELANE (0.42) | KDM4EMAPTHTTALDH1A1GAA | |
| SCHEMBL9055675 | 0.83 | PTGS2 (0.45) | KDM4EMAPTHTTALDH1A1GAA | |
| SCHEMBL9056613 | 0.82 | KDM4E (0.40) | KDM4EMAPTHTTALDH1A1GAA | |
| SCHEMBL8389295 | 0.78 | PTGDR2 (0.44) | KDM4EMAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL8390962 | 0.77 | HTT (0.41) | KDM4EMAPTHTTALDH1A1GAA | |
| SCHEMBL9056084 | 0.76 | KDM4E (0.44) | KDM4EMAPTHTTALDH1A1GAA | |
| SCHEMBL8387479 | 0.72 | ELANE (0.44) | KDM4EMAPTHTTALDH1A1LMNA | |
| SCHEMBL8801802 | 0.72 | ELANE (0.42) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8802237 | 0.71 | MEN1 (0.47) | KDM4EMAPTHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |