Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 6/20 | 0.38 |
| ▸ | THRA | P10827 | 5/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057704 | 0.91 | MEN1 (0.42) | ELANETHRBTHRAEDNRBEDNRA | |
| SCHEMBL9056342 | 0.89 | ELANE (0.42) | ELANEEDNRBEDNRATP53MAPT | |
| SCHEMBL8387054 | 0.82 | THRB (0.46) | THRBTHRAS1PR3MAPTKDM4E | |
| SCHEMBL8801975 | 0.78 | ELANE (0.44) | ELANETHRBTHRAS1PR3MAPT | |
| SCHEMBL8802237 | 0.78 | MEN1 (0.47) | ELANEEDNRBEDNRAMAPTKDM4E | |
| SCHEMBL9057939 | 0.76 | MEN1 (0.47) | ELANEEDNRBEDNRAMAPTKDM4E | |
| SCHEMBL8388506 | 0.75 | THRB (0.46) | THRBTHRAS1PR3MAPTKDM4E | |
| SCHEMBL9056901 | 0.75 | MEN1 (0.42) | ELANEEDNRBEDNRAMAPTKDM4E | |
| SCHEMBL8807382 | 0.75 | ELANE (0.44) | ELANEEDNRBEDNRAMAPTKDM4E | |
| SCHEMBL9056902 | 0.75 | MEN1 (0.42) | ELANEEDNRBEDNRAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |