SCHEMBL9056515

SCHEMBL9056515

CCCCCCCCC(OC(=O)c1cc[c]cc1)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
MLYCD O95822 1/20 0.37
CTSK P43235 2/20 0.36
PNLIP P16233 2/20 0.36
TSHR P16473 1/20 0.36
FAAH O00519 5/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
PRSS1 P07477 2/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
CTSG P08311 1/20 0.34
CTRB1 P17538 1/20 0.34
CMA1 P23946 1/20 0.34
CES1 P23141 3/20 0.34
CES2 O00748 1/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058971 1.00 ALDH1A1 (0.40) ALDH1A1MLYCDCTSKPNLIPTSHR
SCHEMBL9126844 0.92 NPC1 (0.43) ALDH1A1PNLIPTSHRNPC1MAPT
SCHEMBL9057419 0.90 ALDH1A1 (0.39) ALDH1A1MLYCDCTSKPNLIPTSHR
SCHEMBL8536761 0.85 TP53 (0.48) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL8603999 0.85 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1
SCHEMBL9127457 0.85 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1
SCHEMBL6002317 0.85 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1
SCHEMBL7529388 0.85 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1
SCHEMBL9222370 0.85 TP53 (0.48) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL8605430 0.85 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332392-B1 Dioxane liquid crystal compounds SHOWA SHELL SEKIYU (JP) 1994-12-07 EP claimed
EP-0350330-B1 LIQUID CRYSTAL COMPOUNDS Showa Shell Sekiyu Kabushiki Kaisha (JP) 1992-11-11 EP claimed
JP-1316372-A None JP disclosed
EP-0327349-B1 Liquid crystal compounds SHOWA SHELL SEKIYU (JP) 1996-04-10 EP disclosed
US-5433887-A Liquid crystal compounds SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1995-07-18 US disclosed
US-5110496-A LIQUID CRYSTAL COMPOUND SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1992-05-05 US disclosed
EP-0445037-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-09-04 EP disclosed
JP-H01316372-A DIOXANE-BASED LIQUID CRYSTAL SUBSTANCE SHOWA SHELL SEKIYU KK 1989-12-21 JP disclosed