SCHEMBL9057419

SCHEMBL9057419

CCCCCCCCC(OC(=O)c1cc[c]cc1)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MLYCD O95822 2/20 0.36
CTSK P43235 3/20 0.35
PNLIP P16233 2/20 0.35
TSHR P16473 1/20 0.35
FAAH O00519 4/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
PRSS1 P07477 2/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
CTSG P08311 1/20 0.33
CTRB1 P17538 1/20 0.33
CMA1 P23946 1/20 0.33
CES1 P23141 2/20 0.33
CES2 O00748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9056515 0.90 ALDH1A1 (0.40) ALDH1A1MLYCDCTSKPNLIPTSHR
SCHEMBL9058971 0.90 ALDH1A1 (0.40) ALDH1A1MLYCDCTSKPNLIPTSHR
SCHEMBL9126844 0.82 NPC1 (0.43) ALDH1A1PNLIPTSHRNPC1MAPT
SCHEMBL9407615 0.80 ALDH1A1 (0.58) ALDH1A1PNLIPTSHRFAAHNPC1
SCHEMBL8605437 0.80 ALDH1A1 (0.58) ALDH1A1PNLIPTSHRFAAHNPC1
SCHEMBL17845803 0.80 ALDH1A1 (0.58) ALDH1A1PNLIPTSHRFAAHNPC1
SCHEMBL9056406 0.77 NPC1 (0.53) ALDH1A1TSHRNPC1MAPTPRSS1
SCHEMBL6002317 0.75 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1
SCHEMBL9222370 0.75 TP53 (0.48) ALDH1A1TSHRMAPT
SCHEMBL7529388 0.75 PNLIP (0.49) ALDH1A1MLYCDPNLIPTSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327349-B1 Liquid crystal compounds SHOWA SHELL SEKIYU (JP) 1996-04-10 EP claimed
EP-0327349-B1 Liquid crystal compounds SHOWA SHELL SEKIYU (JP) 1996-04-10 EP disclosed