Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452292 | 1.00 | ALDH5A1 (0.56) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL21843753 | 0.80 | ALDH5A1 (0.54) | ALDH5A1ABATMAPTKMT2AALDH1A1 | |
| SCHEMBL4862884 | 0.80 | CES2 (0.50) | MAPTKMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL1193448 | 0.80 | MEN1 (0.53) | MAPTKMT2AHTTCA1CA2 | |
| SCHEMBL11490236 | 0.80 | MEN1 (0.53) | MAPTKMT2AHTTCA1CA2 | |
| SCHEMBL8420807 | 0.80 | CES2 (0.50) | MAPTALDH1A1LMNAHPGDCA1 | |
| SCHEMBL14842658 | 0.80 | TPMT (0.48) | ALDH5A1ABATKMT2AALDH1A1LMNA | |
| SCHEMBL5469788 | 0.80 | CES2 (0.50) | MAPTALDH1A1LMNAHPGDCA1 | |
| SCHEMBL12997454 | 0.80 | MEN1 (0.53) | MAPTKMT2AHTTCA1CA2 | |
| SCHEMBL14842660 | 0.80 | TPMT (0.48) | ALDH5A1ABATKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349090-A | Process for preparing arylketoamines | HOECHST CELANESE CORPORATION (US) | 1994-09-20 | — | — | US | claimed |
| US-5338884-A | Reacting an arylisonitrosoalkanone with hydrogen then acid, ester inpresence of catalyst | HOECHST CELANESE (US) | 1994-08-16 | — | — | US | claimed |
| US-5319142-A | Process for preparing substituted and unsubstituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1994-06-07 | — | — | US | claimed |
| US-5220063-A | Reacting arylisonitrosoalkanone with hydrogen and acyl doner in presence of transition metal catalyst | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | claimed |
| US-5198585-A | Catalytic hydrogenation of arylisonitrosoalkanone | HOECHST CELANESE CORPORATION (US) | 1993-03-30 | — | — | US | claimed |
| WO-1993001158-A1 | METHOD FOR THE PREPARATION OF ARYLKETOAMINES | HOECHST CELANESE CORPORATION (US) | 1993-01-21 | — | — | WO | claimed |
| US-5175368-A | Hydrogenating aryl alpha-oximinoalkyl ketones in aqueous medium containing hydrochlroic acid, recovering salt | HOECHST CELANESE CORPORATION (US) | 1992-12-29 | — | — | US | claimed |
| EP-0491557-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-06-24 | — | — | EP | claimed |
| EP-0481705-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-04-22 | — | — | EP | claimed |
| US-5041669-A | Reacting alkyl aryl ketones with alkyl nitrites, extracting product, catalytically hydrogenating/reducing in nonaqueous acid mixture | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | claimed |
| JP-4295450-A | — | — | None | — | — | JP | disclosed |
| WO-1996012709-A1 | SUBSTITUTED BIPHENYL PYRAZINES | HOECHST CELANESE CORPORATION (US) | 1996-05-02 | — | — | WO | disclosed |
| WO-1996012750-A1 | POLYMER COMPOSITIONS CONTAINING SUBSTITUTED BIPHENYL PYRAZINES | HOECHST CELANESE CORPORATION (US) | 1996-05-02 | — | — | WO | disclosed |
| US-5466873-A | Reacting acetophenone with nitrosonium compound in presence of water and acid to make phenylglyoxal | HOECHST CELANESE CORPORATION (US) | 1995-11-14 | — | — | US | disclosed |
| US-5464923-A | Polymer blends for paints | HOECHST CELANESE CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0491557-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5124489-A | Process for preparing phenethanol ethers by the reduction of corresponding phenylglyoxal acetals | HOECHST CELANESE CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| US-5041669-A | Reacting alkyl aryl ketones with alkyl nitrites, extracting product, catalytically hydrogenating/reducing in nonaqueous acid mixture | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0383539-A1 | Production of alpha-chloro-alpha-oximino-4-hydroxy-acetophenone | HOECHST CELANESE CORPORATION (US) | 1990-08-22 | — | — | EP | disclosed |
| US-3966813-A | Process for the preparation of 1-(m- and p-hydroxyphenyl)-2-aminoethanol | WARNER-LAMBERT COMPANY (US) | 1976-06-29 | — | — | US | disclosed |