Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810832 | 0.82 | G6PC1 (0.46) | G6PC1 | |
| SCHEMBL9057190 | 0.78 | CYP1A2 (0.57) | CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8818077 | 0.77 | G6PC1 (0.44) | CYP19A1G6PC1 | |
| SCHEMBL9056764 | 0.76 | G6PC1 (0.41) | G6PC1 | |
| SCHEMBL9056641 | 0.75 | G6PC1 (0.40) | CYP19A1G6PC1 | |
| SCHEMBL9062965 | 0.75 | G6PC1 (0.40) | CYP19A1MAPTG6PC1 | |
| SCHEMBL8812187 | 0.70 | G6PC1 (0.46) | CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24323034 | 0.69 | G6PC1 (0.51) | G6PC1 | |
| SCHEMBL8172289 | 0.69 | G6PC1 (0.51) | G6PC1 | |
| SCHEMBL9057773 | 0.69 | MC4R (0.46) | G6PC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |