Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | AGER | Q15109 | 3/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056764 | 0.82 | G6PC1 (0.41) | G6PC1AGERMTNR1AL3MBTL1TSHR | |
| SCHEMBL8810832 | 0.79 | G6PC1 (0.46) | G6PC1AGERMTNR1AL3MBTL1HTT | |
| SCHEMBL8818077 | 0.77 | G6PC1 (0.44) | G6PC1CYP19A1AGERMTNR1AL3MBTL1 | |
| SCHEMBL9056534 | 0.75 | CYP19A1 (0.51) | G6PC1CYP19A1 | |
| SCHEMBL9062965 | 0.75 | G6PC1 (0.40) | G6PC1CYP19A1AGERMTNR1AL3MBTL1 | |
| SCHEMBL24323034 | 0.69 | G6PC1 (0.51) | G6PC1AGERMTNR1AL3MBTL1HTT | |
| SCHEMBL8172289 | 0.69 | G6PC1 (0.51) | G6PC1AGERMTNR1AL3MBTL1HTT | |
| SCHEMBL9057773 | 0.69 | MC4R (0.46) | G6PC1AGERMTNR1AUSP2HPGD | |
| SCHEMBL7885548 | 0.68 | G6PC1 (0.54) | G6PC1AGERMTNR1ATSHRUSP2 | |
| SCHEMBL515999 | 0.68 | G6PC1 (0.54) | G6PC1AGERMTNR1ATSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |