SCHEMBL9056709

SCHEMBL9056709

Cc1nn(C)c(Cl)c1S(=O)(=O)Oc1cc(C(=O)O)cc2c1OC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACLY P53396 2/20 0.39
LMNA P02545 2/20 0.33
GAA P10253 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CNR1 P21554 5/20 0.32
FPR2 P25090 2/20 0.32
PROKR1 Q8TCW9 2/20 0.32
SRD5A1 P18405 1/20 0.32
SRD5A2 P31213 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CCR2 P41597 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
MCL1 Q07820 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9057622 0.78 CYP1A2 (0.42) GAACYP1A2CYP3A4CYP2C9CNR1
SCHEMBL9056672 0.76 TSHR (0.33) LMNAMAPTCNR1SMN1; SMN2L3MBTL1
SCHEMBL9058376 0.75 PTGS2 (0.43) ACLYLMNAMAPTFPR2PROKR1
SCHEMBL9057824 0.75 CNR1 (0.37) CNR1SRD5A1SRD5A2SMN1; SMN2ALDH1A1
SCHEMBL9062931 0.75 PTPN1 (0.39) ACLYLMNAMAPTCNR1SMN1; SMN2
SCHEMBL9058121 0.74 ITGA1 (0.49) ACLY
SCHEMBL9062688 0.74 MAPT (0.35) GAAMAPTCNR1SRD5A2L3MBTL1
SCHEMBL9054762 0.73 CNR2 (0.36) LMNAMAPTCNR1SMN1; SMN2ALDH1A1
SCHEMBL7814338 0.72 CA12 (0.44) LMNACNR1ALDH1A1
SCHEMBL9062465 0.72 ALDH1A1 (0.50) LMNAGAAMAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed