Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27262314 | 0.87 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL27262316 | 0.87 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL10484687 | 0.76 | L3MBTL1 (0.33) | L3MBTL1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11892711 | 0.73 | L3MBTL1 (0.36) | L3MBTL1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL9052242 | 0.71 | L3MBTL1 (0.35) | L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10882735 | 0.69 | MME (0.32) | — | |
| SCHEMBL12224198 | 0.68 | L3MBTL1 (0.39) | L3MBTL1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11603642 | 0.68 | ACE (0.36) | — | |
| SCHEMBL4326048 | 0.68 | ACE (0.36) | — | |
| SCHEMBL14023905 | 0.68 | L3MBTL1 (0.33) | L3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002241-A9 | USE OF NITROGEN OXIDE SPECIES AND ADDUCTS TO INHIBIT SKELETAL MUSCLE CONTRACTION | — | 1996-02-29 | — | — | WO | claimed |
| WO-1996003139-A1 | USE OF NITRIC OXIDE OR NITRIC OXIDE ADDUCTS TO PRESERVE PLATELETS | DUKE UNIVERSITY (US) | 1996-02-08 | — | — | WO | claimed |
| WO-1996002241-A1 | USE OF NITROGEN OXIDE SPECIES AND ADDUCTS TO INHIBIT SKELETAL MUSCLE CONTRACTION | DUKE UNIVERSITY (US) | 1996-02-01 | — | — | WO | claimed |