Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL9056160 | 0.80 | ALOX15 (0.50) | ALOX15HSD17B10 | |
| Aconitic Acid SCHEMBL6273427 | 0.77 | KDM4E (0.75) | KDM4ETSHRALOX15HSD17B10 | |
| Aconitic Acid SCHEMBL8650635 | 0.77 | KDM4E (0.75) | KDM4ETSHRALOX15HSD17B10 | |
| Aconitic Acid SCHEMBL6273429 | 0.77 | KDM4E (0.75) | KDM4ETSHRALOX15HSD17B10 | |
| SCHEMBL9054271 | 0.77 | KDM4E (0.44) | KDM4ETSHRALOX15HSD17B10 | |
| Aconitic Acid SCHEMBL27092737 | 0.75 | TSHR (0.78) | KDM4ETSHRALOX15HSD17B10 | |
| Aconitic Acid SCHEMBL31252804 | 0.75 | KDM4E (0.86) | KDM4ETSHRALOX15HSD17B10 | |
| SCHEMBL9054490 | 0.74 | ABCC4 (0.38) | — | |
| Aconitic Acid SCHEMBL27092730 | 0.73 | TSHR (0.82) | KDM4ETSHRALOX15HSD17B10 | |
| Aconitic Acid SCHEMBL22334 | 0.73 | TSHR (1.00) | KDM4ETSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446636-B1 | External application base or auxiliary agent and external application composition for human being or animal containing the same | SHOWA DENKO KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5455042-A | Ointment comprising a homogenous mixture of a polymer or copolymer of N-vinylacetamide, water and/or alcohols, and a pharmacologically active component | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-10-03 | — | — | US | disclosed |
| US-5344655-A | Drug delivery | SHOWA DENKO K.K. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5254338-A | N-vinylacetamide polymer | SHOWA DENKO K.K. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0446636-A2 | External application base or auxiliary agent and external application composition for human being or animal containing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-09-18 | — | — | EP | disclosed |