Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763920 | 0.88 | KMT2A (0.54) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL10907507 | 0.82 | LMNA (0.61) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL11666243 | 0.82 | KMT2A (0.50) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL26924223 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL22265096 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL11500222 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL9638536 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL11480093 | 0.80 | GAA (0.52) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL14276944 | 0.80 | KMT2A (0.54) | KMT2AALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL329955 | 0.80 | ALDH1A1 (0.49) | KMT2AALDH1A1HSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384026-A | Preparation method of phenylacetic acid compound | 台州臻挚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022262686-A1 | KRAS G12D INHIBITORS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |
| EP-3781575-A1 | MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS | Ascentage Pharma (Suzhou) Co., Ltd. (CN) | 2021-02-24 | — | — | EP | disclosed |
| WO-2020151738-A1 | MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2020-07-30 | — | — | WO | disclosed |
| WO-1996012706-A1 | NOVEL ACID PYRAZOLE AND PYRAZOLONE DERIVATIVES FOR USE AS ENDOTHELIN RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1996-05-02 | — | — | WO | disclosed |