Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801465 | 0.75 | SLC22A6 (0.40) | KDM4EALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8803144 | 0.72 | SLC22A6 (0.41) | KDM4EALDH1A1HPGDHTTRAB9A | |
| SCHEMBL21479880 | 0.70 | GSK3B (0.49) | KDM4EHPGDHTTMAPTTP53 | |
| SCHEMBL9055605 | 0.69 | KDM4E (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL9057701 | 0.69 | HTT (0.49) | KDM4EALDH1A1HPGDHTTRAB9A | |
| SCHEMBL8388289 | 0.67 | SLC22A6 (0.48) | KDM4EALDH1A1HPGDHTTRAB9A | |
| SCHEMBL12708461 | 0.67 | KDM4E (0.56) | KDM4EALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL9055602 | 0.67 | GABRP (0.35) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8389032 | 0.66 | PPARG (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL8803045 | 0.66 | MAPT (0.37) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |