Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648939 | 0.87 | HRH2 (0.57) | PRMT6NPC1RAB9AMAPTROCK2 | |
| SCHEMBL4892800 | 0.82 | PRMT6 (1.00) | PRMT6LMNATSHRRECQLHTT | |
| SCHEMBL8647793 | 0.81 | ATP4A (0.65) | — | |
| SCHEMBL3607745 | 0.80 | ROCK2 (0.56) | HTTNPC1RAB9AMAPTROCK2 | |
| SCHEMBL8648287 | 0.80 | ROCK2 (0.56) | HTTNPC1RAB9AMAPTROCK2 | |
| SCHEMBL3052495 | 0.79 | PRMT6 (0.69) | PRMT6LMNATSHRRECQLHTT | |
| SCHEMBL8648948 | 0.79 | ATP4A (0.53) | PRMT6NPC1RAB9AROCK2ROCK1 | |
| SCHEMBL8648946 | 0.79 | ATP4A (0.53) | PRMT6NPC1RAB9AROCK2ROCK1 | |
| SCHEMBL27562786 | 0.78 | PRMT6 (0.57) | PRMT6LMNATSHRRECQLHTT | |
| SCHEMBL23742621 | 0.78 | MAPT (0.50) | NPC1RAB9AMAPTROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |