Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12927452 | 0.85 | ALDH1A1 (0.44) | NCF1ALDH1A1TDP1 | |
| SCHEMBL7589847 | 0.80 | NCF1 (0.37) | NCF1ATML3MBTL1 | |
| SCHEMBL14093037 | 0.80 | NCF1 (0.37) | NCF1ATML3MBTL1 | |
| SCHEMBL11989609 | 0.80 | NCF1 (0.37) | NCF1ATML3MBTL1 | |
| SCHEMBL12927447 | 0.79 | — | — | |
| SCHEMBL24608310 | 0.77 | NCF1 (0.33) | NCF1 | |
| SCHEMBL13713126 | 0.76 | ATM (0.41) | NCF1ALDH1A1ATML3MBTL1 | |
| SCHEMBL731727 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1ATM | |
| SCHEMBL733216 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1ATM | |
| SCHEMBL9939993 | 0.73 | NCF1 (0.36) | NCF1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158708-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-06-08 | — | — | US | disclosed |
| WO-2017046603-A1 | ANTIBACTERIAL COMPOUNDS AND NEW USES THEREOF | REDX PHARMA PLC (GB) | 2017-03-23 | — | — | WO | disclosed |
| WO-2017046606-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-03-23 | — | — | WO | disclosed |
| WO-2016067009-A1 | COMPOUNDS WITH ACTIVITY AGAINST BACTERIA AND MYCOBACTERIA | REDX PHARMA PLC (GB) | 2016-05-06 | — | — | WO | disclosed |
| WO-2015155549-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015114317-A1 | 5H-ISOTHIAZOLO[4,5-C]PYRIDINE-3,4-DIONE OR 5H-PYRAZOLO[4,3-C]PYRIDIN-3,4-DIONE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-08-06 | — | — | WO | disclosed |
| US-8946422-B2 | 8-methoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones and related compounds as anti-infective agents | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8129533-B2 | Method for production of quinolone-containing lyophilized preparation | DALICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129533-B2 | Method for production of quinolone-containing lyophilized preparation | DALICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-7875722-B2 | having high antibacterial activity and high safety, at high yield and in a simple manner; one-pot process | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-01-25 | — | — | US | disclosed |
| US-7875722-B2 | having high antibacterial activity and high safety, at high yield and in a simple manner; one-pot process | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20100063279-A1 | METHOD FOR PRODUCING QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20100063279-A1 | METHOD FOR PRODUCING QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20090306035-A1 | Compounds and Methods for modulating the Silencing of a Polynucleotide of Interest | EMORY UNIVERSITY (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306035-A1 | Compounds and Methods for modulating the Silencing of a Polynucleotide of Interest | EMORY UNIVERSITY (US) | 2009-12-10 | — | — | US | disclosed |
| US-7582627-B2 | 3-Amino-7-[3-(1-aminoethyl)-4-fluoropyrrolidin-1-yl]-1-cyclopropyl-8-methyl-1H-pyrido[4,3-d]pyrimidine-2,4-dione; quinolone antibiotics; bactericides; for antibiotic- resistant bacterial infections, ciprofloxacin- resistant ones; inhibiting wild-type and quinolone- resistant mutants of DNA gryase | WARNER-LAMBERT COMPANY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20080300403-A1 | Method for Production of Quinolone-Containing Lyophilized Preparation | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-12-04 | — | — | US | disclosed |
| US-20080300403-A1 | Method for Production of Quinolone-Containing Lyophilized Preparation | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158708-A1 | ANTIBACTERIAL COMPOUNDS | ABCC1, SLC11A2, NQO2 | NCF1 379/4885ALDH1A1 1408/4885TDP1 4346/4885 |
| US-20080300403-A1 | Method for Production of Quinolone-Containing Lyophilized Preparation | NQO2, TREH, CYP51A1 | NCF1 1645/4885ALDH1A1 3893/4885TDP1 2721/4885 |
| US-20090306035-A1 | Compounds and Methods for modulating the Silencing of a Polynucleotide of Interest | SNRPE, NSUN2, SNRPA | NCF1 553/4885ALDH1A1 3615/4885TDP1 164/4885 |
| US-20100063279-A1 | METHOD FOR PRODUCING QUINOLONE CARBOXYLIC ACID DERIVATIVE | NQO2, QPCT, QARS1 | NCF1 849/4885ALDH1A1 1079/4885TDP1 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.