Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810366 | 0.84 | ROCK2 (0.55) | GAANPSR1ROCK2 | |
| SCHEMBL8814244 | 0.84 | GAA (0.44) | GAANPSR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL8809779 | 0.84 | GAA (0.52) | GAANPSR1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9056512 | 0.84 | KDM4E (0.36) | GAANPSR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL9056936 | 0.82 | GAA (0.50) | GAANPSR1ALDH1A1SMN1; SMN2LTB4R2 | |
| SCHEMBL8817897 | 0.82 | GAA (0.47) | GAANPSR1ALDH1A1KDM4EROCK2 | |
| SCHEMBL8817749 | 0.81 | NPSR1 (0.49) | GAANPSR1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8807180 | 0.81 | GAA (0.49) | GAANPSR1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8808422 | 0.81 | TP53 (0.52) | GAANPSR1ALDH1A1TP53POLB | |
| SCHEMBL8817744 | 0.81 | NPSR1 (0.45) | GAANPSR1ALDH1A1SMN1; SMN2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |