Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476467 | 0.92 | G6PC1 (0.54) | SLC6A2SLC6A4SLC6A3G6PC1S1PR1 | |
| SCHEMBL10891206 | 0.89 | G6PC1 (0.50) | CYP2C19SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL11693064 | 0.85 | S1PR1 (0.48) | SLC6A2SLC6A4SLC6A3G6PC1S1PR1 | |
| SCHEMBL8806703 | 0.84 | G6PC1 (0.48) | SLC6A2SLC6A4SLC6A3G6PC1S1PR1 | |
| SCHEMBL9057596 | 0.84 | AGER (0.57) | SLC6A2SLC6A4SLC6A3G6PC1S1PR1 | |
| SCHEMBL8809151 | 0.84 | AGER (0.57) | CYP2C19SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL28104378 | 0.84 | G6PC1 (0.48) | CYP2C19SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL6553676 | 0.81 | G6PC1 (0.44) | CYP2C19SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL4312492 | 0.79 | SLC6A2 (0.55) | CYP2C19SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL8809383 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3G6PC1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |