Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476467 | 0.92 | G6PC1 (0.54) | AGERSLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL10891206 | 0.89 | G6PC1 (0.50) | AGERSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL8806703 | 0.84 | G6PC1 (0.48) | AGERSLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL9057640 | 0.84 | CYP2C19 (0.53) | SLC6A2SLC6A4SLC6A3CYP2C19G6PC1 | |
| SCHEMBL28104378 | 0.84 | G6PC1 (0.48) | AGERSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL9057596 | 0.84 | AGER (0.57) | AGERSLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL6553676 | 0.81 | G6PC1 (0.44) | AGERSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL11504078 | 0.80 | CYP2D6 (0.55) | AGERSLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4306682 | 0.79 | NOS2 (0.62) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL2931103 | 0.76 | REN (0.66) | AGERSLC6A2SLC6A4SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |