Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056322 | 0.89 | CSF1R (0.38) | CSF1RMPOTPOKCNH2TP53 | |
| SCHEMBL8130696 | 0.89 | GABRA2 (0.42) | ALDH1A1TSHRNPC1KCNH2GABRA2 | |
| SCHEMBL10587033 | 0.88 | GABRA2 (0.41) | ALDH1A1TSHRNPC1KCNH2TP53 | |
| SCHEMBL8802989 | 0.84 | PTGDR2 (0.34) | ALDH1A1TSHRNPC1TP53GABRA2 | |
| SCHEMBL8801606 | 0.84 | HDAC1 (0.34) | ALDH1A1TSHRNPC1TP53KMT2A | |
| SCHEMBL9056955 | 0.83 | LMNA (0.38) | CSF1RALDH1A1TSHRKMT2AHTT | |
| SCHEMBL9056315 | 0.83 | CSF1R (0.42) | CSF1RALDH1A1MPOTPOKCNH2 | |
| SCHEMBL7103475 | 0.81 | EPHA2 (0.42) | ALDH1A1TSHRNPC1GABRA2GABRB2 | |
| SCHEMBL7823482 | 0.79 | LMNA (0.45) | ALDH1A1TSHRNPC1KMT2AHTT | |
| SCHEMBL9058665 | 0.78 | KMT2A (0.42) | CSF1RALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |