Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGAV | P06756 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056480 | 0.76 | F2 (0.42) | F2MAPT | |
| SCHEMBL9054863 | 0.73 | F2 (0.40) | ITGB3ITGAVITGA2BF2LMNA | |
| SCHEMBL9055918 | 0.71 | F2 (0.43) | ITGB3ITGAVITGA2BF2MMP1 | |
| SCHEMBL9055222 | 0.70 | F2 (0.58) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9056979 | 0.69 | F2 (0.57) | ITGB3ITGAVITGA2BF2SCN9A | |
| SCHEMBL9057064 | 0.68 | F2 (0.51) | ITGB3ITGAVITGA2BF2GAA | |
| SCHEMBL9055048 | 0.68 | F2 (0.53) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055067 | 0.68 | F2 (0.75) | F2 | |
| SCHEMBL9057068 | 0.67 | F2 (0.51) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9054638 | 0.66 | F2 (0.51) | ITGB3ITGAVITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |