Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054863 | 0.90 | F2 (0.40) | F2ALDH1A1MAPTTSHRHTR6 | |
| SCHEMBL9057064 | 0.84 | F2 (0.51) | F2MAPTALOX15TSHRHPGD | |
| SCHEMBL9055918 | 0.83 | F2 (0.43) | F2 | |
| SCHEMBL9055264 | 0.83 | F2 (0.43) | F2ALDH1A1MAPTHTR7HTR6 | |
| SCHEMBL9055655 | 0.83 | F2 (0.39) | F2ALDH1A1MAPTHTR7HTR6 | |
| SCHEMBL9055273 | 0.81 | MAPT (0.39) | ALDH1A1MAPTTSHRHTR7HTR6 | |
| SCHEMBL9062397 | 0.80 | ALDH1A1 (0.42) | F2ALDH1A1MAPTALOX15TSHR | |
| SCHEMBL9059238 | 0.77 | F2 (0.43) | F2 | |
| SCHEMBL9055255 | 0.76 | HTR6 (0.36) | F2ALDH1A1MAPTHTR7HTR6 | |
| SCHEMBL9057780 | 0.76 | ITGB3 (0.39) | F2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |