Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.36 |
| ▸ | ITGAV | P06756 | 7/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055655 | 0.93 | F2 (0.39) | F2HTR6ITGB3ITGAVITGA2B | |
| SCHEMBL9056480 | 0.90 | F2 (0.42) | F2HTR6MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9055255 | 0.86 | HTR6 (0.36) | F2HTR6ITGB3ITGAVITGA2B | |
| SCHEMBL9055918 | 0.80 | F2 (0.43) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9055946 | 0.77 | HTR6 (0.33) | F2HTR6ITGB3ITGAVITGA2B | |
| SCHEMBL9058635 | 0.76 | F2 (0.34) | F2HTR6ITGB3ITGAVITGA2B | |
| SCHEMBL9055123 | 0.75 | ITGB3 (0.44) | ITGB3ITGAVITGA2B | |
| SCHEMBL9057064 | 0.75 | F2 (0.51) | F2ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL9059238 | 0.74 | F2 (0.43) | F2 | |
| SCHEMBL9055264 | 0.74 | F2 (0.43) | F2HTR6MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |