Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | CCR10 | P46092 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055985 | 0.87 | F2 (0.54) | F2ITGB3ITGAVITGA2BCCR10 | |
| SCHEMBL9055048 | 0.86 | F2 (0.53) | F2ITGB3ITGAVITGA2BCCR10 | |
| SCHEMBL9056463 | 0.86 | F2 (0.44) | F2GAAMAPTNPSR1TSHR | |
| SCHEMBL9056480 | 0.84 | F2 (0.42) | F2MAPTTSHRALOX15HPGD | |
| SCHEMBL9056467 | 0.84 | ITGB3 (0.43) | F2GAAMAPTNPSR1TSHR | |
| SCHEMBL9057068 | 0.84 | F2 (0.51) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9055222 | 0.82 | F2 (0.58) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9055898 | 0.82 | ITGB3 (0.46) | GAAMAPTNPSR1TSHRITGB3 | |
| SCHEMBL9055067 | 0.82 | F2 (0.75) | F2 | |
| SCHEMBL9054913 | 0.81 | ALDH1A1 (0.43) | F2GAAMAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |