Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DVL1 | O14640 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9062779 | 0.99 | DVL1 (0.49) | DVL1RXRARXRBRXRGPIM2 | |
| SCHEMBL9257663 | 0.81 | DVL1 (0.43) | DVL1PIM2HRH3FFAR1FFAR4 | |
| SCHEMBL9053391 | 0.81 | DVL1 (0.44) | DVL1RXRARXRBRXRGPIM2 | |
| Hydrochloric Acid SCHEMBL9057996 | 0.80 | DVL1 (0.45) | DVL1RXRARXRBRXRGPIM2 | |
| Hydrochloric Acid SCHEMBL9057948 | 0.80 | DVL1 (0.56) | DVL1RXRARXRBRXRGPIM2 | |
| SCHEMBL9257661 | 0.79 | DVL1 (0.42) | DVL1PIM2HRH3FFAR1FFAR4 | |
| SCHEMBL9250797 | 0.78 | FFAR1 (0.43) | DVL1RXRARXRBRXRGHRH3 | |
| SCHEMBL9259291 | 0.78 | SPNS2 (0.44) | DVL1RXRARXRBRXRGHRH3 | |
| SCHEMBL9055061 | 0.78 | S1PR1 (0.48) | DVL1RXRARXRBRXRGHRH3 | |
| SCHEMBL9256853 | 0.77 | FFAR1 (0.43) | RXRARXRBRXRGHRH3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | claimed |