Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 10/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057506 | 0.92 | RHEB (0.47) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL9057087 | 0.88 | HTR1A (0.49) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL13309274 | 0.80 | HTR1B (0.52) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL7084585 | 0.80 | HTR1B (0.52) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL3790955 | 0.77 | HTR1B (0.54) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL3794323 | 0.76 | HTR1B (0.55) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL10591822 | 0.76 | HTR1A (0.55) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL7079421 | 0.76 | HTR1B (0.52) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL502401 | 0.73 | HTR1B (0.52) | RHEBHTR1AHTR1BADRB2ADRB1 | |
| SCHEMBL13003014 | 0.73 | HTR1A (0.50) | RHEBHTR1AHTR1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022290-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |