Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.43 |
| ▸ | KDR | P35968 | 6/20 | 0.43 |
| ▸ | AR | P10275 | 8/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057600 | 0.78 | TSHR (0.33) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL8811275 | 0.73 | POLB (0.34) | NR3C2TSHR | |
| SCHEMBL9055863 | 0.70 | TSHR (0.33) | KCNA3TSHR | |
| SCHEMBL5542387 | 0.70 | TSHR (0.45) | TSHR | |
| SCHEMBL9056994 | 0.69 | TSHR (0.34) | NR3C2KCNA3TSHR | |
| SCHEMBL9056947 | 0.68 | SLC6A2 (0.42) | — | |
| SCHEMBL28015765 | 0.67 | TSHR (0.39) | TSHR | |
| SCHEMBL9057232 | 0.66 | MAPT (0.36) | KCNA3TSHR | |
| SCHEMBL8013258 | 0.65 | NR3C2 (0.51) | ARNR3C2HDAC1KCNA3TSHR | |
| Ethylene SCHEMBL11428459 | 0.65 | NR3C2 (0.53) | NR3C2HDAC1KCNA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |