Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056994 | 0.71 | TSHR (0.34) | MAPTLMNATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9055863 | 0.69 | TSHR (0.33) | MAPTLMNATSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9062683 | 0.69 | G6PC1 (0.36) | MAPTKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8811275 | 0.68 | POLB (0.34) | MAPTKDM4ELMNAHTTTSHR | |
| SCHEMBL9057600 | 0.67 | TSHR (0.33) | MAPTKDM4ELMNATSHRKMT2A | |
| SCHEMBL5542387 | 0.66 | TSHR (0.45) | MAPTKDM4ETSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9056943 | 0.66 | CYP2C19 (0.37) | MAPTKDM4ELMNAHTTTSHR | |
| SCHEMBL9058015 | 0.66 | FGFR1 (0.43) | TSHRKCNA3 | |
| SCHEMBL18593133 | 0.65 | CYP11B1 (0.32) | TSHRKCNA3 | |
| SCHEMBL28015765 | 0.63 | TSHR (0.39) | MAPTLMNAHTTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |