Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397352 | 0.73 | MAPT (0.33) | MAPT | |
| Water SCHEMBL6938407 | 0.71 | HSD11B1 (0.32) | MAPT | |
| SCHEMBL3418488 | 0.69 | MAPT (0.31) | MAPT | |
| SCHEMBL19083712 | 0.69 | HSD11B1 (0.32) | MAPT | |
| SCHEMBL40305 | 0.69 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL4858945 | 0.69 | MAPT (0.31) | MAPT | |
| SCHEMBL1237995 | 0.69 | LMNA (0.38) | SLC22A2SLC22A1GRIN2DGRIN3BLMNA | |
| SCHEMBL14411565 | 0.69 | MAPT (0.31) | MAPT | |
| SCHEMBL17352397 | 0.69 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL4612492 | 0.69 | HSD11B1 (0.31) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8157485-A | — | — | None | — | — | JP | disclosed |
| JP-H08157485-A | NEW ORGANOSILICON COMPOUND | SHOWA DENKO KK | 1996-06-18 | — | — | JP | disclosed |