Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058203 | 1.00 | CA2 (0.44) | CA2CA4PSEN1PSEN2APH1B | |
| SCHEMBL9058827 | 0.86 | CA2 (0.47) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950394 | 0.77 | CA2 (0.46) | CA2CA4 | |
| Hydrochloric Acid SCHEMBL8950390 | 0.77 | CA2 (0.46) | CA2CA4 | |
| SCHEMBL9057829 | 0.70 | KDM1A (0.37) | CA2 | |
| SCHEMBL9115575 | 0.70 | CA2 (0.46) | CA2CA4 | |
| SCHEMBL9057893 | 0.70 | CA2 (0.50) | CA2CA4 | |
| SCHEMBL9117323 | 0.68 | CA2 (0.44) | CA2CA4 | |
| SCHEMBL9058838 | 0.68 | CA2 (0.49) | CA2CA4 | |
| SCHEMBL9058849 | 0.68 | CA2 (0.39) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022099-A1 | OPHTHALMIC COMPOSITIONS FOR TREATING GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |