Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112920 | 0.80 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1RXFP1CYP2D6HTT | |
| SCHEMBL8946084 | 0.71 | GAA (0.48) | ALDH1A1L3MBTL1HTTTACR1KCNJ11 | |
| SCHEMBL12862996 | 0.70 | KDM4E (0.62) | ALDH1A1CYP2D6MAPK14HDAC1HDAC7 | |
| SCHEMBL13776424 | 0.70 | HSP90AA1 (0.43) | ALDH1A1RXFP1MEN1KMT2A | |
| SCHEMBL13015660 | 0.70 | KIF11 (0.52) | ALDH1A1L3MBTL1TACR1KCNJ11KDM4E | |
| SCHEMBL4121438 | 0.69 | MEN1 (0.46) | ALDH1A1RXFP1TRPV1KDM4EMEN1 | |
| SCHEMBL8687043 | 0.69 | HTT (0.52) | L3MBTL1CYP2D6HTTTRPV1KCNJ11 | |
| SCHEMBL14146416 | 0.69 | RXFP1 (0.47) | ALDH1A1L3MBTL1RXFP1ADRA2CADRB1 | |
| SCHEMBL14568587 | 0.69 | CFTR (0.51) | ALDH1A1L3MBTL1TACR1HDAC1KDM4E | |
| SCHEMBL14146163 | 0.68 | RXFP1 (0.46) | ALDH1A1L3MBTL1RXFP1CYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | disclosed |