Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058563 | 0.82 | MKNK1 (0.35) | MKNK1PIM1DYRK3CCNA2CDK2 | |
| SCHEMBL9058720 | 0.82 | MKNK1 (0.35) | MKNK1PIM1DYRK3CCNA2CDK2 | |
| SCHEMBL9058877 | 0.81 | CYP1A2 (0.33) | DYRK3CCNA2CDK2DYRK1ADYRK2 | |
| SCHEMBL9058274 | 0.79 | THRB (0.32) | MKNK1PIM1DYRK3CCNA2CDK2 | |
| SCHEMBL9058560 | 0.79 | MKNK1 (0.34) | MKNK1PIM1DYRK3CCNA2CDK2 | |
| SCHEMBL9058711 | 0.79 | MKNK1 (0.34) | MKNK1PIM1DYRK3CCNA2CDK2 | |
| SCHEMBL11734584 | 0.78 | CYP1A2 (0.43) | MKNK1PIM1CYP1A2CYP2C9GLA | |
| SCHEMBL9058865 | 0.76 | CYP1A2 (0.33) | DYRK3CCNA2CDK2DYRK1ADYRK2 | |
| SCHEMBL9059217 | 0.75 | ALDH1A1 (0.35) | MKNK1CYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL9058715 | 0.75 | MKNK1 (0.39) | MKNK1PIM1KCNH2DYRK3CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016656-A1 | CONDENSED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-06 | — | — | WO | claimed |