Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.32 |
| ▸ | ITGAV | P06756 | 9/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058635 | 0.89 | F2 (0.34) | HTR6ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055273 | 0.86 | MAPT (0.39) | HTR6MAPT | |
| SCHEMBL9055255 | 0.85 | HTR6 (0.36) | HTR6ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055609 | 0.81 | ITGB3 (0.36) | ITGB3ITGAVITGA2BF2MAPT | |
| SCHEMBL9055655 | 0.81 | F2 (0.39) | HTR6ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055821 | 0.81 | CCR10 (0.35) | ITGB3ITGAVITGA2B | |
| SCHEMBL9055310 | 0.80 | F2 (0.40) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9054863 | 0.77 | F2 (0.40) | HTR6ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9054934 | 0.76 | F2 (0.46) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055264 | 0.76 | F2 (0.43) | HTR6F2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |