Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9062192 | 0.99 | ITGB3 (0.37) | ITGB3ITGA2BHRH3KCNH2L3MBTL3 | |
| Hydrochloric Acid SCHEMBL9062149 | 0.83 | TP53 (0.37) | HRH3KDM4EALDH1A1TP53TDP1 | |
| Hydrochloric Acid SCHEMBL9061661 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2BHRH3KCNH2L3MBTL3 | |
| SCHEMBL27485031 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BF2RTPSAB1TPSD1 | |
| Hydrochloric Acid SCHEMBL27485387 | 0.77 | ITGB3 (0.59) | ITGB3ITGA2BF2RTPSAB1TPSD1 | |
| SCHEMBL14640812 | 0.77 | GABRA5 (0.40) | ITGB3ITGA2B | |
| Acetic Acid Methyl Ester SCHEMBL27500032 | 0.77 | HRH3 (0.34) | HRH3KCNH2L3MBTL3L3MBTL1TP53 | |
| Hydrochloric Acid SCHEMBL8485313 | 0.76 | TPSAB1 (0.36) | HRH3L3MBTL3L3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31463606 | 0.75 | GABRA5 (0.39) | ITGB3ITGA2B | |
| SCHEMBL3564651 | 0.75 | ITGB3 (0.37) | ITGB3ITGA2BHRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | claimed |
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |