Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.58 |
| ▸ | HTR1D | P28221 | 11/20 | 0.58 |
| ▸ | HTR1B | P28222 | 11/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057945 | 0.84 | HTR1A (0.74) | HTR1AHTR1DHTR1BMTNR1BSLC6A9 | |
| SCHEMBL9058520 | 0.79 | HTR1A (0.79) | HTR1AHTR1DHTR1BMTNR1BSLC6A9 | |
| SCHEMBL6307506 | 0.74 | HTR1A (0.61) | HTR1AHTR1DHTR1BMTNR1BKDM4E | |
| SCHEMBL9058797 | 0.74 | HTR1A (0.67) | HTR1AHTR1DHTR1BMTNR1BKDM4E | |
| SCHEMBL6000211 | 0.73 | HTR1A (0.75) | HTR1AHTR1DHTR1BMTNR1BKDM4E | |
| SCHEMBL9057938 | 0.73 | HTR1A (0.66) | HTR1AHTR1DHTR1BMTNR1BKCNH2 | |
| SCHEMBL9058894 | 0.73 | HTR1A (0.72) | HTR1AHTR1DHTR1BKDM4EALDH1A1 | |
| SCHEMBL9054738 | 0.73 | HTR1A (0.81) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL8566993 | 0.72 | HTR1A (0.73) | HTR1AHTR1DHTR1BMTNR1BSLC6A9 | |
| SCHEMBL9058832 | 0.72 | HTR1A (0.65) | HTR1AHTR1DHTR1BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012713-A1 | NOVEL NAPHTHYLPIPERAZINE-DERIVED AROMATIC ETHERS FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | claimed |