Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.75 |
| ▸ | HTR1D | P28221 | 9/20 | 0.75 |
| ▸ | HTR1B | P28222 | 9/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314991 | 0.89 | HTR1A (0.64) | HTR1AHTR1DHTR1BMTNR1BKDM4E | |
| SCHEMBL6306333 | 0.88 | HTR1A (0.60) | HTR1AHTR1DHTR1BMTNR1BDRD4 | |
| SCHEMBL8566993 | 0.87 | HTR1A (0.73) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| SCHEMBL1738849 | 0.84 | HTR5A (0.63) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| SCHEMBL9287039 | 0.84 | HTR1A (0.62) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| SCHEMBL9284653 | 0.84 | HTR1A (0.62) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| SCHEMBL9204835 | 0.84 | HTR1A (0.59) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| SCHEMBL6313399 | 0.84 | HTR1A (0.69) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| Hydrochloric Acid SCHEMBL9639755 | 0.83 | HTR1A (0.61) | HTR1AHTR1DHTR1BMTNR1BHTR6 | |
| Hydrochloric Acid SCHEMBL5253513 | 0.83 | HTR5A (0.62) | HTR1AHTR1DHTR1BMTNR1BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1603395-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080170-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
| US-5821245-A | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1998-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | CBR3, L3MBTL3, BRS3 | HTR1A 2209/4885HTR1D 970/4885HTR1B 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.