Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031413 | 0.86 | ITGB3 (0.54) | TRPV6ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8314973 | 0.84 | ITGB3 (0.39) | ALDH1A1KDM4EACHEITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7682728 | 0.83 | ITGB3 (0.39) | ALDH1A1KDM4EACHEITGB3ITGA2B | |
| SCHEMBL9030136 | 0.82 | RAB9A (0.39) | ACHEITGB3ITGA2B | |
| SCHEMBL27499700 | 0.82 | ALDH1A1 (0.51) | TRPV6ALDH1A1KDM4EMAPTHPGD | |
| Hydrochloric Acid SCHEMBL9029951 | 0.81 | RAB9A (0.39) | ACHEITGB3ITGA2B | |
| SCHEMBL9030618 | 0.79 | TP53 (0.47) | LMNAITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9030762 | 0.78 | TP53 (0.46) | LMNAITGB3ITGA2B | |
| SCHEMBL9031663 | 0.77 | ITGB3 (0.37) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9032372 | 0.77 | ITGB3 (0.37) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | claimed |
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |