Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 11/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGAV | P06756 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055821 | 0.90 | CCR10 (0.35) | CCR10ITGB3ITGAVITGA2B | |
| SCHEMBL9056498 | 0.82 | CCR10 (0.49) | CCR10 | |
| SCHEMBL9055028 | 0.79 | CCR10 (0.39) | CCR10ITGB3ITGAVITGA2B | |
| SCHEMBL9055946 | 0.75 | HTR6 (0.33) | ITGB3ITGAVITGA2B | |
| SCHEMBL9055273 | 0.74 | MAPT (0.39) | — | |
| SCHEMBL9056609 | 0.73 | CCR10 (0.45) | CCR10 | |
| SCHEMBL9055502 | 0.71 | F2 (0.40) | ITGB3ITGAVITGA2B | |
| SCHEMBL9057565 | 0.69 | F2 (0.42) | — | |
| SCHEMBL9055707 | 0.69 | CCR10 (0.44) | CCR10ITGB3ITGAVITGA2B | |
| SCHEMBL9058474 | 0.69 | F2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |