Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055264 | 0.90 | F2 (0.43) | MAPTHTR7HTR6ALDH1A1HPGD | |
| SCHEMBL9062397 | 0.87 | ALDH1A1 (0.42) | MAPTHTR7HTR6ALDH1A1HPGD | |
| SCHEMBL9055946 | 0.86 | HTR6 (0.33) | MAPTHTR6 | |
| SCHEMBL9055255 | 0.82 | HTR6 (0.36) | MAPTHTR7HTR6ALDH1A1HPGD | |
| SCHEMBL9056480 | 0.81 | F2 (0.42) | MAPTHTR7HTR6ALDH1A1HPGD | |
| SCHEMBL9059446 | 0.78 | F2 (0.53) | — | |
| SCHEMBL9055617 | 0.78 | F2 (0.44) | — | |
| SCHEMBL9055403 | 0.78 | F2 (0.44) | — | |
| SCHEMBL9056467 | 0.78 | ITGB3 (0.43) | MAPTHTR7ALDH1A1HPGDTSHR | |
| SCHEMBL9054379 | 0.78 | F2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |