Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 1.00 |
| ▸ | HTR3A | P46098 | 4/20 | 0.76 |
| ▸ | HTR6 | P50406 | 2/20 | 0.76 |
| ▸ | DRD2 | P14416 | 2/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.76 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.76 |
| ▸ | HTR3B | O95264 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | DRD3 | P35462 | 1/20 | 0.76 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.76 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 5/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR5A | P47898 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396943 | 0.86 | HTR3A (1.00) | HTR7HTR3AHTR6DRD2ADRB1 | |
| SCHEMBL6366499 | 0.86 | HTR3A (1.00) | HTR7HTR3AHTR6DRD2ADRB1 | |
| SCHEMBL379 | 0.86 | HTR3A (1.00) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Hydrochloric Acid SCHEMBL29397565 | 0.85 | LMNA (1.00) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Bromide SCHEMBL27797305 | 0.85 | HTR3A (0.96) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Hydrochloric Acid SCHEMBL246416 | 0.85 | LMNA (1.00) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Piperazine SCHEMBL28843777 | 0.85 | HTR3A (0.96) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Hydrochloric Acid SCHEMBL6602545 | 0.85 | LMNA (1.00) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Iodide SCHEMBL27505006 | 0.83 | HTR3A (0.93) | HTR7HTR3AHTR6DRD2ADRB1 | |
| Hydrochloric Acid SCHEMBL9069817 | 0.83 | HTR3A (0.93) | HTR7HTR3AHTR6DRD2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |