Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058880 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BLIMK2ACHE | |
| SCHEMBL9058853 | 0.80 | ACHE (0.47) | ACHE | |
| SCHEMBL26668467 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BACHE | |
| SCHEMBL250597 | 0.71 | ACHE (0.63) | ITGB3ITGA2BACHE | |
| SCHEMBL4501690 | 0.71 | ACHE (0.77) | ACHE | |
| SCHEMBL9062199 | 0.69 | ACHE (0.59) | ACHE | |
| SCHEMBL12736115 | 0.64 | PDK1 (0.47) | ITGB3ITGA2B | |
| SCHEMBL6011640 | 0.64 | NMT1 (0.42) | ITGB3ITGA2B | |
| SCHEMBL2745655 | 0.63 | TRPV1 (0.49) | — | |
| SCHEMBL4777856 | 0.62 | GBA1 (0.51) | LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022280-A1 | N-SUBSTITUTED 1-ACYLAMINOALKYL PIPERIDINES FOR TREATMENT OF CEREBRAL DISORDERS AND DEPRESSIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-25 | — | — | WO | disclosed |