Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368699 | 0.86 | MAPT (0.35) | ALDH1A1SMN1; SMN2MAPTNPSR1TSHR | |
| SCHEMBL27410262 | 0.83 | TSHR (0.39) | ALDH1A1NPSR1TSHRTDP1CYP3A4 | |
| SCHEMBL5607925 | 0.83 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL21802487 | 0.80 | HTT (0.34) | MAPK1 | |
| SCHEMBL20332132 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP2D6SMN1; SMN2GLO1MAPT | |
| SCHEMBL4325428 | 0.75 | CYP2D6 (0.43) | ALDH1A1CYP2D6SMN1; SMN2GLO1MAPT | |
| SCHEMBL3956082 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP2D6SMN1; SMN2GLO1MAPT | |
| SCHEMBL29022492 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP2D6SMN1; SMN2GLO1MAPT | |
| SCHEMBL28684972 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP2D6SMN1; SMN2GLO1MAPT | |
| SCHEMBL21427204 | 0.75 | GLO1 (0.47) | ALDH1A1CYP2D6SMN1; SMN2GLO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996008255-A1 | TRANSDERMAL DEVICE FOR DELIVERY OF LEVONORGESTREL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-03-21 | — | — | WO | disclosed |