Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058790 | 0.83 | ALDH1A1 (0.43) | TSHRCYP3A4TDP1ALDH1A1NPSR1 | |
| SCHEMBL368699 | 0.80 | MAPT (0.35) | TSHRCYP3A4TDP1ALDH1A1NPSR1 | |
| SCHEMBL5607925 | 0.78 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL21802487 | 0.75 | HTT (0.34) | — | |
| SCHEMBL75001 | 0.70 | TSHR (0.63) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL821284 | 0.70 | TSHR (0.34) | TSHRTDP1ALDH1A1 | |
| SCHEMBL561780 | 0.70 | TSHR (0.34) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4420666 | 0.69 | TSHR (0.41) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL11963780 | 0.69 | TSHR (0.35) | TSHRTDP1ALDH1A1 | |
| SCHEMBL589664 | 0.69 | TSHR (0.35) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124287-A1 | COMPOUNDS FOR TREATING VIRAL INFECTION | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2024-06-20 | — | — | WO | disclosed |