Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058242 | 0.87 | ACHE (0.56) | KMT2AMEN1TSHRACHECHRM4 | |
| Hydrochloric Acid SCHEMBL8479949 | 0.81 | KMT2A (0.62) | KMT2AMEN1TSHRACHECHRM4 | |
| SCHEMBL9058559 | 0.80 | KMT2A (0.58) | KMT2AMEN1TSHRACHECHRM4 | |
| SCHEMBL3599380 | 0.78 | ACHE (0.69) | KMT2AMEN1TSHRACHESMN1; SMN2 | |
| SCHEMBL9058966 | 0.78 | ACHE (0.60) | ACHECHRM4SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5080239 | 0.77 | KMT2A (0.78) | KMT2AMEN1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27528589 | 0.77 | ITGB3 (0.60) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL3959065 | 0.76 | ACHE (0.66) | KMT2AACHECHRM4SMN1; SMN2ALDH1A1 | |
| SCHEMBL2793889 | 0.76 | KMT2A (0.77) | KMT2AMEN1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4464843 | 0.76 | ACHE (0.62) | KMT2AMEN1TSHRACHECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |