Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599380 | 0.94 | ACHE (0.69) | ACHESMN1; SMN2RECQLKDM4EALDH1A1 | |
| SCHEMBL641232 | 0.92 | ACHE (0.56) | ACHESMN1; SMN2RECQLCHRM4KDM4E | |
| SCHEMBL639999 | 0.92 | ACHE (0.56) | ACHESMN1; SMN2RECQLCHRM4KDM4E | |
| SCHEMBL640904 | 0.92 | ACHE (0.56) | ACHESMN1; SMN2RECQLCHRM4KDM4E | |
| SCHEMBL642022 | 0.87 | SIGMAR1 (0.55) | ACHESMN1; SMN2RECQLKDM4EALDH1A1 | |
| SCHEMBL3709310 | 0.86 | RECQL (0.70) | ACHESMN1; SMN2RECQLKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3706762 | 0.84 | RECQL (0.68) | ACHESMN1; SMN2RECQLKDM4EALDH1A1 | |
| SCHEMBL2850013 | 0.84 | ALDH1A1 (0.70) | SMN1; SMN2KDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4797625 | 0.84 | SIGMAR1 (0.69) | ACHESMN1; SMN2RECQLTSHR | |
| SCHEMBL4467334 | 0.84 | SMN1; SMN2 (0.61) | ACHESMN1; SMN2RECQLCHRM4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538111-B2 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2009-05-26 | — | — | US | disclosed |
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LTB4R2, BDKRB2, TBXA2R | ACHE 188/4885SMN1; SMN2 1897/4885RECQL 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.