Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233013 | 0.86 | AVPR2 (0.64) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL5269822 | 0.85 | AVPR2 (0.61) | AVPR2AVPR1AHPGDALDH1A1MAPT | |
| SCHEMBL7314107 | 0.80 | HPGD (0.44) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL5236885 | 0.77 | ALDH1A1 (0.46) | HPGDALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19454368 | 0.77 | ALDH1A1 (0.43) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL19454365 | 0.76 | ALDH1A1 (0.43) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7313684 | 0.75 | AVPR2 (0.79) | AVPR2AVPR1A | |
| SCHEMBL5233449 | 0.75 | CRBN (0.44) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL22722545 | 0.75 | AVPR2 (0.41) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL19454362 | 0.74 | ALDH1A1 (0.42) | AVPR2AVPR1AHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |