Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 9/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060152 | 0.74 | ALDH1A1 (0.50) | LMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4367939 | 0.72 | CA1 (0.52) | LMNAALDH1A1MAPK1 | |
| SCHEMBL4367872 | 0.72 | CA1 (0.52) | LMNAALDH1A1MAPK1 | |
| SCHEMBL4369186 | 0.72 | CA1 (0.52) | LMNAALDH1A1MAPK1 | |
| SCHEMBL6815835 | 0.71 | ALDH1A1 (0.47) | LMNASMN1; SMN2ALDH1A1CTSDMAPK1 | |
| SCHEMBL5154554 | 0.71 | LMNA (0.42) | LMNAALDH1A1CXCR3CTSDMAPK1 | |
| SCHEMBL5155145 | 0.71 | CYP2B6 (0.39) | CDK8CLK4LMNACXCR3CTSD | |
| SCHEMBL11797566 | 0.70 | POLB (0.57) | LMNAPOLBHTTALDH1A1KDM4E | |
| SCHEMBL5154955 | 0.70 | CTSD (0.38) | CDK8CLK4LMNACXCR3CTSD | |
| SCHEMBL6544322 | 0.70 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1CTSDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017840-A1 | HETEROCYCLYL SUBSTITUTED HYDROXYACETAMIDE DERIVATIVES AS FONGICIDES | AGREVO UK LIMITED (GB) | 1996-06-13 | — | — | WO | disclosed |